Diagnostic Pathology of Ovarian Tumors by Robert A. Soslow M.D. (auth.), Robert A. Soslow, Carmen

By Robert A. Soslow M.D. (auth.), Robert A. Soslow, Carmen Tornos (eds.)

Diagnostic Pathology of Ovarian Tumors deals a spotlight at the pathology of ovarian neoplasia with unique clinically suitable details for practising pathologists no longer present in different extra basic volumes of gynecologic pathology. this significant paintings focuses virtually completely on techniques for exact prognosis and histologic subclassification, and the medical correlates of those diagnoses. It offers evolving guidance for detecting early ovarian melanoma in prophylactic specimens; state of the art info on bettering the reproducible and clinically significant subclassification of ovarian carcinoma in addition to new proposals for ovarian carcinoma grading. Richly illustrated, containing ample tables and figures in addition to bulleted issues of data, Diagnostic Pathology of Ovarian Tumors is the 1st textual content providing chapters written via training gynecologists on how scientific information can improve pathologic diagnostic accuracy, how pathologists can successfully express their diagnostic critiques to gynecologists, and how within which a given analysis triggers a cascade of scientific checking out and remedy.

Diagnostic Pathology of Ovarian Tumors can be of significant worth to training surgical pathologists, together with gynecologic pathologists, pathology citizens in education, in addition to gynecologic and scientific oncologists all over the world.

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22 Primary endometrioid carcinoma of ovary with squamous metaplasia. (a) Frozen section. (b) Permanent section. 25. 26). Since the cytologic appearance of these three tumors is different, an appreciation of these features can help in the differential diagnosis. A scraping at the time of FS can be very helpful. 26). 27). 28a–c). Endometrioid variant of yolk sac tumor is rare and is seen in young patients, age 11–34 (mean, 22 years). The age is a helpful diagnostic feature. Features that favor the diagnosis of yolk sac 28 C.

C) Frozen section of the same tumor mimicking a metastasis extensive lymphovascular invasion, preservation of normal structures with invasion in between them (Fig. 18). 16 (a) Frozen section of a primary ovarian mucinous carcinoma showing a characteristic complex glandular papillary pattern with mucin depletion. 20a, b). 18 Features that favor metastatic carcinoma to the ovary if the tumor has endometrioid features • Bilateral multinodular solid masses • Involvement of ovarian surface • Nodular invasive growth • Extensive lymphovascular invasion • Extensive desmoplastic stroma • Preservation of normal structures • Uniform histology • Extensive necrosis • Segmental destruction of glands • Garland pattern with cribriform architecture + dirty necrosis • Low grade architecture with high nuclear grade • Occasional goblet cells • Metastases to mesentery and/or liver Fig.

Ovarian mature teratomas with mucinous epithelial neoplasms: morphologic heterogeneity and association with pseudomyxoma peritonei. Am J Surg Pathol. 2008;32:645–55. 21. Roth LM, Liban E, Czernobilski B. Ovarian endometrioid carcinomas mimicking Sertoli and Sertoli-Leydig cell tumors. Cancer. 1982;50:1322–31. 22. Young RH, Prat J, Scully RE, et al. Ovarian endometrioid carcinomas resembling sex-cord stromal tumors. A clinicopathological analysis of 13 cases. Am J Surg Pathol. 1982;6:513–22. 23.

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