Brain Acetylcholine and Neuropsychiatric Disease by D. S. Janowsky, J. M. Davis (auth.), Kenneth L. Davis,

By D. S. Janowsky, J. M. Davis (auth.), Kenneth L. Davis, Philip A. Berger (eds.)

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247-262, Stratton, New York. A. BERGER ET AL. , 1978, Cholinergic inhibition of methylphenidate induced stereotypy with oxotremorine, Psychopharmacology 56: 1. , 1973, Induction of severe depression by physostigmine in marijuana intoxicated individuals, Br. J. Addict. 68:321. , and Munoz, R, 1972, Diagnostic criteria for use in psychiatric research, Arch. Gen. Psychiatry 26:57. , 1973, A dopaminergic-cholinergic mechanism in production of psychotic symptoms, BioI. Psychiatry 6: 165. , 1954, Mental depression in hypertensive patients treated for long periods with large doses of reserpine, N.

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Seven of the 16 patients developed depression, in two of these individuals the depression was described as severe. Five patients developed schizophrenic-like reactions without a major depressive component. All 16 subjects had impaired memory and concentration. , 1964). Subjects with blood cholinesterase activity 40% below control values were reported to be Significantly more depressed, more anxious, more confused and less energetic when compared to those subjects whose cholinesterase activity was not decreased to 40% of control values.

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